By the early 20th century the bridge had become too small to handle the increasing railway traffic and the construction of a new, larger bridge started in 1907. The new bridge, named Hohenzollernbrücke after the Hohenzollern dynasty, was inaugurated in 1911 by emperor Wilhelm II. The bridge had four railway tracks as well as a two lane road and was supported by three monumental iron truss arches. Massive neo-Roman portals with large towers were built on either side of the bridge, decorated with equestrian statues of kings and emperors.
In 1945, at the end of World War II, the retreating German army blew up all bridges across the Rhine, including the Hohenzollern bridge. Just three years later the bridge was partially repaired and in 1959 the Hohenzollernbrücke was completely reconstructed. The imposing entrances to the bridge were demolished in 1958 and were not replaced.