It was not very long ago that a hand-held shot at low shutter speed and high ISO was unthinkable.
Lens VR coupled with SLR low light capability and improved metering renders very pleasing results nowadays.
Camera technology such as artificial horizion avoids angular distortion.
Editing software such as Photoshop CC is the icing on the cake!
D800, AF-S Nikkor 16-35mm F/4 VR, Handheld
Exposure = 1/30 sec; f/8; ISO 1250@16mm, aperture priority, spot metering