Palazzo da Mula, located in one of the best sections of the Grand Canal, according to a listing by Sotheby's International Realty. Dating back to the start of the 14th century, the building is one of the oldest on the Grand Canal. But the "second piano nobile", so called because it was the second built in the palace, was added at the beginning of the 15th century. The Da Mula family, who built the palazzo and owned it for almost 600 years, were one of the most respected in Venice. Originally from Rome, the Da Mulas were consistent in their support for the watery city when the Italian capital and Venice were at loggerheads. At the entrance there is an original well, which provides further evidence of the family's status as, in general, no one was allowed their own in a bid to prevent the spread of disease