My Maddie is a 8 year old female exotic short hair cat that I adopted back in June of 2003. She was seen recently by my Veterinarian on 11/17/09 for a little bit of an ongoing eye infection. She had 2 weeks earlier been suffering with a mild upper respiratory infection and it was looking like the infection was settling in eyes although all other symptoms were clearing up nicely. No fluorescein stain retention was observed.

Updates:
11/17/09 Physical exam by Veterinarian, negitive for fluorescein stain retention indicating no ulceration of corneas, Neomycin-Poly-Dex Ophthalmic suspension prescribed by Dr, Clavamox Drops prescribed for 14 days by Dr.
Comments: mild eye inflammation mostly in left eye.

11/25/09 Recheck examination by Dr, re-fill prescribed Dr for Neo-Poly-Dex Ophthalmic suspension applied to both eyes 2-3 times a day.
Comments: little or no improvement in eye condition.
12/8/09 Maddie's eye condition is very much worse just within the last 24 hours. I have stopped the Neo-Poly-Dex drops because it has a steroid component. Have to wait two days for appointment with the Veterinarian.

12/10/09 Recheck examination by Dr, positive fluorescein stain retention at this time indicates ulcers in both eyes, left eye appears to be bulging and possibly near rupture, Tonopen/eye pressure check indicated normal, start Cefazolin 50mg/ml, Ciprofloxacin Hydrocloride Ophthalmic solution drops applied 2-3 times a day, continue oral Clavamox Drops.
Comments: Corneal ulcers are now present in both eyes with inflammation, left eye cornea looks like it could be very near rupture, eye pressure ok for both eyes, changed Ophthalmic antibiotic.

12/22/09 Recheck examination by Dr, positive fluorescein stain retention both eyes shows expanding and deepening ulceration of corneas.
Comments: little or no improvement, left eye cornea near rupture.

12/22/09 Consultation with Veterinary Ophthalmologist, positive fluorescein stain retention in both eyes, start Tobramycin Ophthalmic solution b.i.d.
Comments: Change Ophthalmic antibiotic, add 500 mg L-Lysine daily, very little change observed but at least her eye condition has not worsened.

12/28/09 Recheck examination by Dr, positive fluorescein stain retention both eyes, Clavamox Drops continued twice a day.
Comments: little or no improvement.

1/07/10 Recheck examination by Dr, positive fluorescein stain retention in both eyes.
Comments: little or no improvement, Dr abraded corneal surface of right side eye.
The Dr says that this deteriorating eye condition he sees frequently in purebred Persian cats when they come in to him suffering with a viral and or bacterial eye infections. I asked him if this is one of the worse ones he has seen and he said no, many have come in with the cornea already ruptured. I asked if this is more likely a viral infection and he he can't he sure but that the current thinking is that this kind of an eye problem is most likely viral. This one does look like we had some bacterial infection also but that looks like it has now played out. Both our Dr and the Ophthalmologist say this will likely take weeks for her eye condition to improve and that we have to stay alert for signs that her eye condition is again worsening.

1/8/10
Dr says that he may recommend punctuate keratotomy surgery.

1/14/10
Recheck examination by Dr, positive fluorescein stain retention in both eyes. Re-fill Tobramycin Ophthalmic solution b.i.d.
Comments: Ref. updated photos. Left eye has improved with deep ulcer beginning to fill-in, right eye condition is worsening with expanding ulceration on cornea.

2/12/10
Have withheld the antibiotic eye drops for the last ten days.
Today the area of eosinophilic keratitis in her right side eye is either unchanged or a little worse. The left side eye has clearly improved over the last five weeks. See updated photo of today.

2/15/10
Recheck examination by Dr, negitive fluorescein stain retention.
Comments: No uptake of stain in either eye today. Much improvement is seen in the condition of both eyes. Corneal ulcers look to be healing well. Re-filled prescription for Tobramycin Ophthalmic solution for both eyes. See updated (3) photos for Dr C today.

4/1/10
Recheck examination by Dr. Eye Flourescien stain.
No uptake of stain or evidence of ulcers reoccurring. We still see some redness to the white part of the both eyes or uveitis as the Dr describes it but its much improved with the passing 2 months time. We still see a cloudy like film over both her corneas that the Dr says may be scar tissue at this point that will not clear up. The Dr consulted by phone with the veterinary Ophthalmologist and he is recommending that we try adding Cyclopsorine eye drops that will be needed to be compounded by the veterinary pharmacist. The Dr says that Cyclopsorine can have a broad anti-inflammatory effect like a steroid on Maddie's eyes and may help in clearing her eyes further. The Dr does not want to prescribe the anti-inflammatory steroid that we first started with on her eyes back in December. Here is a link for info on Cyclosporine eye drops for cats.
http://www.wedgewoodpetrx.com/learning-center/professional-monographs/cyclosporine-for-veterinary-use.html


5/26/10