Atelopus is a large genus of true toads natively distributed in Costa Rica to Bolivia and French Guiana. Atelopus are generally brightly colored and diurnal. Most species are associated with mid- to high-elevation streams. This genus has been greatly affected by amphibian declines, and many species are now considered endangered, while others already are extinct. The cause of these declines primarily appears to be the chytrid fungus Batrachochytrium dendrobatidis.

Atelopus glyphus is found in Colombia and Panama. Its natural habitats are subtropical or tropical moist montanes and rivers.