The Nazis set up the ghetto in November 1940 in the heart of Warsaw, forcing over 400,000 Jews to live there in inhuman conditions.
In April 1943 Nazi troops entered the ghetto on Heinrich Himmler's orders to liquidate the remaining population of the ghetto. They were attacked by hundreds of fighters for three weeks, the insurgents fought against 3,000 Nazi troops.
After three weeks of fight, the leaders of the uprising were rounded up by the Nazis, most of them committed suicide, including its leader, Mordechai Anilewicz, putting an end to organized resistance.
The Nazis razed the Ghetto to the ground and blew up the city's main synagogue as the symbol of their victory. There were some 50 to 60 thousand people in the ghetto. Some seven thousand were killed or burnt alive during the fights and about 50 thousand were transported to the Treblinka concentration camp.